Journal of Ayurveda and Holistic Medicine (JAHM)

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Randomized, controlled, open-label study of herbal preparation, lekhaneeya mahakashaya ghanavati in dyslipidemia patients

Background: Research over the past 4 decades has consistently shown the burden of dyslipidemia to be very high in terms of morbidity, mortality and medical costs. Dyslipidemia, being a chronic disorder, needs to be managed with safe and effective medicines. The current study compares the efficacy of two herbal preparations, Lekhaneeya Mahakashaya Ghanavati and Shuddha Guggulu Vati in the management of dyslipidemia. Objective: To evaluate and compare the efficacy of Lekhaneeya Mahakashaya Ghanavati versus Shuddha Guggulu Vati in the management of dyslipidemia. Materials and Methods: In this randomized, interventional, active controlled, open-labeled study, a total of 29 dyslipidemic patients were randomly assigned to receive either Lekhaneeya Mahakashaya Ghanavati (LMG; n = 15) or Shuddha Guggulu Vati (SGV; n = 14) for a duration of 4 weeks. The findings with respect to assessment criteria were recorded at baseline and at end of 4 weeks and assessed for the efficacy of the interventions. Results: LMG elicited significant results in Total cholesterol, LDL cholesterol, HDL cholesterol. SGV elicited significant results in Triglycerides. Both the drugs elicited significant results in anthropometric measurements like weight, BMI, various body circumferences and skinfold thickness. However, there was no statistically significant difference between the effects elicited by LMG and SGV on all the parameters. Conclusion: The trial drug, lekhaneeya mahakashaya ghanavati is effective in par with shuddha guggulu vati in the management of dyslipidemia. Further randomized and large multicentric studies are recommended.

Key Words: Ayurveda, Dyslipidemia, Lekhaneeya Mahakashaya Ghanavati; Shuddha Guggulu Vati, Randomized controlled trial

Posted: 2015-09-10More...



 Yoga is a technique towards the improvement of total health by acting on physical and mental level. This present study has been undertaken to examine the effect of Bhastrika Pranayama on breath holding capacity of students. Ten students of B.A.M.S. were randomly registered voluntarily, aged 18- 28 years to participate in this study, from Yoga unit of Swasthavritta department of national institute of Ayurveda, Jaipur, Rajasthan. The breath holding capacity was measured twice before Bhastrika and during Bhastrika. During Bhastrika Pranayama, breath holding capacity was increased near about double of its normal duration. Difference between mean of breath holding time, before and during Bhastrika Pranayama, is about 31.6 and T value is 6.0733 and P value is <0.001 and it is highly significant on statistical parameters. In Bhastrika Pramayama the rate of exchange of air in alveoli and the ventilation at the lower areas of lungs increase, which increases the oxygen and decreases the carbon di-oxide level in blood, which increased the breath retention during the practice of this Pranayama.


KEY WORDS: Bhastrika Pranayama, Breath holding capacity, Yoga.

Posted: 2015-09-10More...

Role of Sarpagandha Vati in Nidranasha (Primary Insomnia)


Context: Insomnia is the most common of all sleep disorders, in which there is inability to fall asleep or to stay asleep as long as desired. In comparison to the therapeutic procedure of different systems of medicine, Ayurveda has good approach towards the treatment of Insomnia in terms of both internal and external therapies. the drug Sarpagandha (Rauwolfia serpentina Benth ex.kuntz) has been widely used in the management of hypertension and insomnia, no study has been carried out to prove its efficacy in insomnia as a single drug.

Aim: To evaluate the efficacy of Sarpagandha Vati in Nidranasha (Primary Insomnia)

Study design: A single group, open labelled, uncontrolled, prospective clinical study with minimum 30 patients with pre and post test design.

Methods and Material:  Study was conducted on 30 patients of Nidranasha (primary Insomnia) who came under inclusion criteria. Sarpagandha tablets of 500mg each prepared with one Bhavana of Sarpagandha Moola Kashaya (root decoction). One tablet was advised in the morning after breakfast and at night bedtime with water for the duration of one month.

Statistical analysis used: Friedman’s test was  used to analyze the significance of change in Subjective parameters. Wilcoxon signed rank test with Bonferroni correction was done for post hoc, to interpret the time of significant change. Paired t test was done to analyze the change in objective parameters.

Results: Highly significant improvements were observed in chief complaints like sleep initiation (p= <0.001), maintaining sleep (p= <0.001) early morning awakening (p=<0.001). Significant improvement were seen in Angamarda (p = <0.001),Shirogaurava (p = <0.001),  Jrumbha (p = <0.001),Tandra(p = <0.001 etc associated complaints from before treatment to after treatment.

Conclusions: The chief mechanism of action of Sarpagandha (Rauwolfia serpentine) seems to be due to its prabhava(specific action or unexplained action).Among other alkaloids reserpine is the one that decides the action of the drug. Hence it can be concluded that Sarpagandha Vati can be effectively used in the management of Nidranasha.


Clinical Trial registration Number: SDMCAH/EC/46/13-14; accepted on 10th April 2013.


Key words: Nidranasha, Insomnia, sleep, Sarpagandha, Rauwolfia serpentina, Hypertension


Posted: 2015-09-10More...

Experimental study of Sushrutokta Jalaprasadana Vidhi with special reference to Gomeda.

Water being a basic need of human being, it is very essential that it stays pure & harmless to health. The water available these days is from various sources. Going through the details of them we come to know that, there are many facets of it we need to think about. As the source changes, the quality of water also differs. The impurities in it are mentioned in Ayurvedic classics as one of the cause for Janapadodhvamsa Vyadhi. To overcome them, many techniques are being adopted. For example, filters, purifiers & chemical agents. Even in Ayurveda, methods of purification of water have been mentioned. Maharshi Sushruta has mentioned seven ways of Jalaprasaadana. It can be considered that things which are mentioned by Maharshi Sushruta were with consideration of the conditions of water in those days. Although whole of the science they had described more than 1000 years back, it is fully applicable even today; so we can’t neglect the possibility that even the purification methods will work today. We also find that there is no elaborate description about the method of using the tools mentioned by Maharshi Sushruta. So the study is meant to explore the Jalaprasadana vidhi with help of Gomeda & try to establish standard for them. Hence to provide essential data & proper validation a study was conducted which is being presented briefly in this paper.

Posted: 2015-09-10More...


Ayurveda is the mother science for all universal sciences. The scope of samhita is vast , hence the thorough understanding of samhita is very essential simultaneously role of tantrayukti, tachchilya, arthasraya etc in understanding samhita is clearly understood. Nyaya (maxims) is one among the other tools through which samhitas can be better understood. Nyayas (maxims) plays a vital role. Hence the present article unravels the importance of nyaya and the steps to be followed to derive the appropriate information using nyayas. The proposed steps are applied and pipeelika bharaharana nyaya, shilaputraka nyaya are analysed in this article.
Posted: 2015-09-10More...

Concept of Krimi in perspective of modern era-A Review

The existence of Krimi is not a new concept. From the Vedic period to Samhita period description of Krimi is found.  Here all visible and invisible Krimi are described.  Though there was no microscope at that period but they felt the existence of invisible Krimi also. Their  mode of transmission, sign and symptom are almost same as worm and microbes in contemporary science. They had given description of structure, naming of Krimi as far as possible. But worms and microbes are described in contemporary science  separately. Acharyas  also described epidemic diseases, contagious diseases in the context of  Janapadodhwamsa and Upasargika Roga.  Keeping these views it is try to describe about concept of Krimi in cotemporary science.
Posted: 2015-09-10More...

A Review of Lodhrasevyadi yoga in the treatment of Lootavisha

Lootavisha or spider poisoning is coming under the group of jangama visha according to Ayurveda. In the classics, lootavisha has been considered as difficult to treat due to its difficulty in diagnosis and severity in nature. Among the clinical features it includes both systemic and local manifestations. In this regard so many medicinal preparations have also been described in the classics. Lodhrasevyadi yoga is such a medicine described by Acharya Vagbhata. In the clinical practice it is found to be very effective for the treatment of any kind of Lootavisha. As it contains maximum sheeta veerya drugs, having madhura rasa and kapha-pittahara property, it can also be used in the dermatological conditions with kapha-pitta predominancy effectively. Again, as all the drugs of this yoga are easily available and not controversial, it can be prepared easily and can be administered in any form to treat any type of spider bite.
Posted: 2015-09-10More...

Eye Donation

Eye is the peripheral organ of sight. Sight is a gift by God but unfortunately the blind people can’t enjoy it. In India approximately 1% of the people are blind and the major causes of blindness include cataract, Glaucoma, refractive errors and corneal blindness. The causes other than corneal blindness are delt satisfactorily. In case of corneal blindness, there are lacunas, keratoplasty is the only option for treatment. The only source of cornea is human donor’s cornea. The demand of cornea is India is almost 1.5 lacks/annum. On the contrary number of cornea retrieval is about 35000 to 50000 per year. There are various misconcepts, lack of knowledge regarding eye donation and regional imbalances (in India) which needs to be minimized. Hence, to meet the increasing demand of corneas to provide vision to corneal blind, it is necessary to make eye donation popular.

This is an attempt to highlight the points regarding eye donation and measures to be taken to accelerate the eye donation by various Government and non Government organizations. These programs should be widely implemented along with the help of religious organization and educational institutes, industry which can increase the awareness of eye donation. Also it needs to strengthen the eye banks, eye surgeons and trained man power for effective counseling, collection of eyeballs and its proper utilization. So every person should pledge to donate eyes and make eye donation popular.

Keywords : Eye donation, eye, cornea, keratoplasty, blindness.

Posted: 2015-09-10More...


Blindness comes with devastating physical condition and deep socio-economic implications. Approximately 45 million people in the world are blind and another 135 million people are deemed to be visually disabled by 2020.

‘Vitamin A’ deficiency alone accounts for 6% among the causes of blindness. It is the chief cause of Childhood Blindness in developing countries.

As a step towards prevention of blindness, the ‘National Programme for Control of Blindness’ recommends a single massive dose of 2,00,000 IU of ‘vitamin A’ orally every 6 months to preschool children and half the dose to children between 6 months to 1year of age.

But, these ‘retinol form’ prophylactic supplements in excess may lead to toxicity causing acute and chronic symptoms, birth defects and even death.

Ayurveda as a science has an equal responsibility in protecting ‘right to sight’ of each individual. Though the classical references does not directly mention about the daily dose of the nutrients, all the drugs mentined as chakshushya, such as Garjara, Karavellaka, Draksha, Shigru, Paalankika etc do contain a large amount of ‘vitamin A’ in them.

Hence an attempt has been made in this article to quantify these classical chakshushya dravya for daily recommended need of ‘vitamin A’ to every individual. 


Posted: 2015-09-12More...

View of Ayurveda students for the Sharir Rachana as subject and the choice of teaching career

Two hundred Ayurveda students were questioned regarding their views on Sharir Rachana as a subject and career option in future. A survey with 10 statements questioner was given to those students and their answers were compiled. The results of this study were encouraging. 95% of students consider Sharir Rachana as an essential subject of medical sciences. A vast majority (92%) felt that a sound knowledge of Sharir Rachana helped them in their clinical rotations in hospitals. Out of them 66% termed the Sharir Rachana as tough subject to understand. About half of them placed Sharir Rachana at par with clinical subjects. In their views, inadequate research facilities and lack of explanation of Ayurvediya Sharir Rachana limits the uptake of Sharir Rachana as a career option.
Posted: 2015-09-10More...

Management of Acute Cerebrovascular Accident through Ayurveda – A Case Study

The global burden of stroke is high, inclusive of increasing incidence, mortality and economic impact, particularly in low and middle income countries. Many researches are being conducted in the field of Ayurveda as well as in contemporary fields for achieving the better line of management for Cerebro Vascular Accident (CVA). This is a case study of an acute CVA. An acute CVA case was admitted on 18.12.2013, with the complaints of loss of strength in the right side of the body, loss of speech, drowsiness since 5 hrs. On examination Glasgowcoma scale was 8/15 (E - 3, M- 4, V-1). Investigation i.e., Computed Tomography scan of head suggested - large acute infarct at left fronto-temporal region involving basal ganglia (middle cerebral artery territory), lipid profile suggested–hyperlipidemia. It was diagnosed as pittakaphaavruta vataja pakshaghata (dakshina). In this case various treatment procedures like cold water pouring over forehead, application of medicated paste on anterior frontanallae, application of shathadhouta ghrutha all over the body, nasal instillation etc with oral medicines were adopted at various condition of the disease. There was a remarkable improvement in the subjective and objective clinical features.

Posted: 2015-09-10More...

Prachhanna and Vanadhanyaka lepa in the management of Indralupta - A case report

Hair is crowning glory and a mark of identity.The scalp and hair diseases are of more importance nowadays due to the cosmetic value in society. Indralupta is a disease among kapalagata roga characterized by loss of hair. Depending on the symptoms in contemporary science we can probably correlate to Alopecia. Prachhanna is explained as one of the raktamokshana procedure indicated in raktaja vyadhi that helps in draining the vitiated rakta. In indralupta there will be vitiation of rakta with kapha which obstructs the hair follicle due to which there will be hair loss. Sushruta mentions that if lepa is applied after prachhanna then better hair growth is obtained.

Posted: 2015-09-10More...

Ayurvedic management of treatment resistant schizophrenia- a case report

Treatment Resistant Schizophrenia (TRS) is clinically challenging disease to treat as the symptoms presented complicate the clinical course of the disease and a large proportion of patients do not reach functional recovery. Till date, Clozapine and augmentating therapy is the only effective medication to treat the disease in contemporary science. In Ayurveda, Sannipataja Unmada management can be taken as guidelines to treat TRS. In the present case, Ayurvedic management like Shodhana and Shamana with Medhya rasayana drugs opened a new possibility to treat the disease & improve the quality of life.

Posted: 2015-09-10More...



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Posted: 2013-11-11 More...
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Vol 3, No 4 (2015): Journal of Ayurveda and Holistic Medicine

Table of Contents

Clinical Study

Randomized, controlled, open-label study of herbal preparation, lekhaneeya mahakashaya ghanavati in dyslipidemia patients PDF
rachna agrawal, Dr. Sarvesh Kumar Agrawal, Dr. Kamalesh Kumar Sharma 24-29
Role of Sarpagandha Vati in Nidranasha (Primary Insomnia) PDF
swathi ajay, Narayana Prakash B, Ajay G S, Suhas Kumar Shetty 30-41

Experimental Study

Experimental study of Sushrutokta Jalaprasadana Vidhi with special reference to Gomeda. PDF

Review Article

Dr.santhosh kumar 53-56
Concept of Krimi in perspective of modern era-A Review PDF
Jeuti Rani Das, Hemanta Bikash Das, Sisir Kumar Mandal, Surendra Kumar Sharma 57-69
A Review of Lodhrasevyadi yoga in the treatment of Lootavisha PDF
Swapna Swayamprava, Niranjan S 70-79
Eye Donation PDF
Govind Vitthalrao Shinde, Mrunal Dattuji Dange, Pallavi Parshuram Lokhande 80-86
Jyoti Ravindra Angadi 87-97
View of Ayurveda students for the Sharir Rachana as subject and the choice of teaching career PDF
Dharmendra Mishra, Shalinee Kumari Mishra 98-107

Case Report

Management of Acute Cerebrovascular Accident through Ayurveda – A Case Study PDF
Totad Muttappa, Vasantha B, Rakesh P Moosath, Vikas Chauhan, Sumit Vinod Kapoor 108-113
Prachhanna and Vanadhanyaka lepa in the management of Indralupta - A case report PDF
Rajani R Sunkad 114-118
Ayurvedic management of treatment resistant schizophrenia- a case report PDF
Madhu Shree 119-128

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