Journal of Ayurveda and Holistic Medicine (JAHM) (eISSN:2321-1563)

Among bests of India, worldwide Ayurveda has its own prominence in perpetuation of healthy life style and   health care. In recent decades global biomedical schools are being attracted to fundamental holistic approach of Ayurveda system of medicine and consequently have engaged themselves for researches to get evidence of quality, safety and efficacy of Ayurvedic medicines on their intrinsic parameters. Publications in support of good pharmaceutics and therapeutics of Ayurveda are not rare now. Every reputed journal of health care is carrying authentic information about Ayurveda. Department of AYUSH of Government of India is taking continuous lead for academic and administrative reforms in this sector. Ten amendments in last four year in chapter IV A of Drugs and Cosmetics Acts and relevant Rules are enough evidence about sincerity of Government for mainstreaming of Ayurvedic medicines.(http://indianmedicine.nic.in/showfile.asp?lid=337 ). But, even after all these academic, administrative and regulatory reforms there are pervasiveness of differential degree of doubts in mind set of elites and commoners as well about Ayurvedic medicines. Quality, standards, stability, safety and true sense therapeutic efficacy of Ayurvedic medicines are under scan of civil society more seriously at present.  Hereby, we fraternity of Ayurvedic medicines will put forward some facts before medicos of country through Institute of Medical Sciences of Banaras Hindu University  to consider and reset their opinion in accordance of new particulars about Ayurvedic medicines.

Background: Pesticides are known for their toxicity on the mammalian system including embryonic development. Cyfluthrin (Trade name: Baygon and Solfac) is used commonly in India and reported to be a teratogenic agent and reported for low birth weight and stunned fetuses (short height), and dooshivishari agada (DVA) commonly use in conditions like garavishajanya dooshivisha.

Aims: To evaluate the efficacy of dooshivishari Agada in cyfluthrin induced Teratogenicity with respect to body weight and height.

Materials & Methods: The 30 pregnant swiss albino mice were divided in to 3 groups of 10 each and 1^st group was control administered with normal saline, 2^nd group given cyfluthrin 32mg/kg body wt, 3^rd group cyfluthrin(32mg/kg body wt) With DVA 1.2gm/kg body wt orally during the organogenesis period i.e. from 5^th to 14^th day.

Statistical analysis used: It was analyzed using student t test using software graph pad prism version 6.

Results: There weights in 1st and 3rd groups are nearly equal and showed the increase of weight and height in3rd group i.e. treated group, weight: Group1-1.24±0.15, Group2-0.68±0.13, and group 3-1±0.11. Height: Group1-2.03±0.23, Group2-1.22±0.28, Group3-1.78±0.21 (Mean± SEM). Comparing the group 2 with group 3 the p value<0.05 in both the criteria’s.

Conclusion: The dooshivishari agada has shown the significant effect in increasing the weight and height of the fetuses which were exposed to the teratogenic agent

Mundi(Sphaeranthus indicus Linn.) is a popularly used drug in the texts of Ayurveda. Whole plant is used in therapeutic conditions like Krimi, Apachi, Yoniroga etc. Hence phyto-pharmacognostic standardization forms the base to start any research. Methods: Authentified, matured, fresh plants were collected and both macro-microscopic characters were documented. Chemical study included physico-chemical screening, preliminary phytochemical test and HPTLC. Results: Pharmacognostic study of leaf showed anisocytic and anomocytic stomata on upper and lower surface respectively and stem part showed unicellular, multicellular, glandular , eglandular types of trichomes. Physicochemical standards and presence of protein, flavanoids, triterpenoid compounds as secondary metabolites, serve as qualitative data related to this drug. Conclusion: The results obtained will prove as standard reference for identification and distinguish it from any admixture.

Keywords: (Mundi, Sphaeranthus indicus, phyto-pharmacognostic, vein-islet number HPTLC) 

Background: From Stone Age to space age the food pattern and life style habits are changing very fast, this change of course is having direct impact over the health. Due to over exertion, suppressing of the natural urges, irregular dieting and depletion of the tissue elements, there is manifestation of ekadasha rupa of shosha. In modern era shosha can be correlated to tuberculosis. It is a major public health problem in India due to the environmental changes, changes in behavioral dietetic habits, poor quality of life, population explosion, under nutrition, and lack of awareness about cause of disease and modern life style. Aims and objectives: To evaluate the role of dietary and lifestyle factors in the pathogenesis of shosha. Methods and materials: An observational study was conducted on 30 patients selected from T.B. Section of Civil Hospital, Bijapur., irrespective of sex, religion, etc., who had presented with the clinical symptoms of tuberculosis. Information on demography, dietary intake and lifestyle factors was collected by standard questionnaires. Results: Sahasaja nidana (over exertion) was found in 40% of patients while, kshayaja nidana (depletion of the tissue) was found in 60% of patients, vega sandaranaja nidana (suppressing of the natural urges) was found in 26.66% of patients.  Nearly 30% of the patients were taking apatarpana ahara. Conclusion:  According to the obtained results the sequential pattern of nidana as it was given in classics has changed the sequence in now a days as vishamashana, kshayaja, sahasaja, sandaranaja. It is because of the changing life style and habits of individual. Trirupa and shad rupa are found in earlier stage of the shosha and ekadasha rupa is in chronic condition of shosha.

Background: Mutrashmari (Urolithiasis)is associated with pain in bladder, testicles and penis, anorexia, Dysuria and fever. Among all the urological problems, most problematic condition is mutrashmari or the urinary calculus. The genesis of the disease can be understood from the fact that it is grouped under the eight most difficult to cure diseases - ashtamahagada.

Aims: To study the disease Urolithiasis in terms of its etiopathogenesis, clinical manifestations with possible correlation to the description available in texts of Ayurveda as well as modern texts. To find out the efficacy of the drug in the management of Mutrashmari symptomatically or by confirming with the use of repeated imaging techniques i.e. Plain X-ray (K.U.B), U.S.G (K.U.B) etc. To study the side effects of drug, if any.

Settings and Design: In the present study, total 36 patients of Mutrashmari were selected and treated into two groups,Group– Ipatients were treated with VarunaGudaorally, in a dose of 10gm. twice daily for two months and in Group- II, 15 patients were under control therapy.

Materials and Method:          

Patients attended the O.P.D. and I.P.D. of Shalya tantra dept.of Rajiv Gandhi Govt. Post Graduate Ayurvedic College & Hospital Paprola, Distt. Kangra (H.P.) provided material for the clinical study.

Results:Out of 17 patients of Vatashmari in Group - 1, 4 patients were cured, 1 patient markedly improved and 12 patients were improved and in control group out of 13 patients of Vatajashmari, 1 was cured, 7 patients were improved and 5 remained unchanged. 1 patient of Pittajashmari was improved and 1 patient of Kaphajashmari remained unchanged.

Conclusion: VarunaGuda has shown encouraging symptomatic relief in most of the clinical features with expulsion of ureteric stones in few cases.

Registration No. 01-AVC-6, August-2004, Himachal Pradesh University, Shimla, H.P.

Whenever two or more drugs are being taken, there is a chance that there will be an interaction among these drugs. These interactions may increase or decrease the effectiveness or may cause serious fatal reactions. The likelihood of drug interactions increases as the number of drugs being taken increases. Therefore, people who take several drugs are at the greatest risk for interactions. It is quite common for a patient to seek herbal treatment while taking several prescription medications. Safety has become a major issue reasonably enough, patients want to know about compatibility and possible interactions when taking herbs and allopathic medicines simultaneously. Such specific questions, unfortunately, are often difficult to answer. This review discusses the issue of drug interactions and several ways to avoid them.

Urbanization in India is growing exponentially as a consequence of Globalization and economic development.  The contributing factors of urbanization are availability of better opportunities for job, education, health services, housing and transportation. Despite these beneficial factors urbanization also poses many health hazards to humans. Vicharchika is one of them. This study is carried out with aim to determine the role of urbanization in the manifestation of vicharchika (eczema) and to found out solution to prevent the same. Habitat wise distribution of 268 patients of vicharchika (eczema) registered for various theses of IPGT & RA were analyzed statistically and found that out of 268 patients of vicharchika (eczema) registered for study in various theses, 179 patients were from urban habitat. The possible cause of this higher incidence of vicharchika in urban area is reviewed critically by going through various literature and information on internet. The causes of this high incidence are found to be due to the unhygienic availability, access and utilization of food articles in the cities. Inclination of urbanized people towards outside food is also a major cause of dietary incompatibility (Viruddha Ahara) which is a major cause of vicharchika (eczema). High level of stressors like violence, financial crisis, rising inflation rate, lack of social support etc also leads to abnormality of psychoneuroimmunological system leading to triggering and exacerbation of skin hypersensitivity like vicharchika (eczema). Future research potential in the field of urbanization and genesis of vicharchika (eczema) are also suggested.

Though population of the world is increasing day by day yet 20-30% populations of the world are the victims of the infertility. In India, 1 out of 10 couples suffer from infertility and    about half of cases, men alone are contributory. Causes of Infertility are being impaired sperm production, or its function, impaired sperm delivery, due to vicious life style and environmental exposure. Oligoastheoteratazoosperima syndrome is the condition commonly prevailing and is concerned with semen production and function.  In Ayurveda, Shukra dushti is considered to be the main cause for the male infertility. Absence or production of less quantity of semen is the main feature and explains 8 pathological entities which damages normal composition of semen. Vajikarana (Aphrodisiac therapy) is the specialized branch of Ayurveda dealing with Shukra Dushti and Klaibya (Semen disorders and Sexual Dysfunction). Though it mainly concentrates on Shukra dosha (seminal disorders) and Vandhyatwa (Infertility), but it also emphasizes about Vyadhi (Different pathologies), Functions of Dosha, Dhatu, Mala, Agni, (Metabolic conditions);  Manas,- (Psychosomatic conditions); lifestyles and Poorvajanma kruta karma (Deeds of previous life).  Srushti Fertility center is the specialty OPD which is attending the cases of infertility since 07yrs.the statistic revealed that, Out of 10 cases of Male infertility, 1-2 cases are diagnosed as OAT Syndrome. By proper counseling one can correct their skepticism about the thoughts of infertility; treatment is planned based on Pratipursuha siddhanta(theory of Individuality). Here is the presentation of 20 cases of OAT Syndrome coming under different types Shukra dushti.